Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4625)
Related Products (4625)
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4-Methylsalicylic acid
0 Images4-Methylsalicylic acid is a methyl derivative of Salicylic acid (HY-B0167). 4-Methylsalicylic acid derivatives inhibit the activity of alkaline phosphatases such as TNAP and IAP. 4-Methylsalicylic acid derivatives exhibit immunosuppressive activity.
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Fmoc-Ser-OMe
0 ImagesSynonyms: Fmoc-L-Ser-OMeFmoc-Ser-OMe (Fmoc-L-Ser-OMe) is an Fmoc-protected L-serine methyl ester and also a solid-phase peptide synthesis intermediate. Fmoc-Ser-OMe is linked to Ellman resin via its hydroxyl side chain. Fmoc-Ser-OMe is used in peptide synthesis.
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Methyl 1H-pyrrole-2-carboxylate
0 ImagesMethyl 1H-pyrrole-2-carboxylate is a drug intermediate that can act as an acyl donor. Methyl 1H-pyrrole-2-carboxylate can be synthesized into a series of pyrrolidine derivatives through tranesterification reactions with various alcohols.
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N-tert-Boc-cis-4-fluoro-L-proline
0 ImagesN-tert-Boc-cis-4-fluoro-L-proline (Compound 11) is a drug intermediate for the synthesis of 4-fluoropyrrolidine-2-carbonitrile DPP-4 inhibitor. N-tert-Boc-cis-4-fluoro-L-proline can be used to study type 2 diabetes.
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2-(Pyridin-2-yl)acetic acid hydrochloride
0 Images2-(Pyridin-2-yl)acetic acid hydrochloride is a heterocyclic aromatic carboxylic acid compound. 2-(Pyridin-2-yl)acetic acid hydrochloride can be used as an organic synthesis intermediate or a metal complex.
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2'-O-MB-cAMP sodium
0 ImagesSynonyms: 2'-O-Monobutyryl cyclic AMP sodium2'-O-MB-cAMP (2'-O-Monobutyryl cyclic AM) sodium is an activatable proagent of Cyclic AMP (HY-B1511).
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5-Iodo-cytidine
0 ImagesSynonyms: 5-Iodo-D-cytidine5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analog that acts as an intermediate in organic synthesis. 5-Iodo-cytidine serves as a chemically modified nucleotide to replace partial cytidine residues in in vitro transcription, enhancing the translation efficiency and stability of chemically modified mRNA. Purine nucleoside analogs exhibit broad anti-tumor activity and target indolent lymphoid malignancies. 5-Iodo-cytidine can be used in mRNA therapy and tumor-related research.
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Polyvinylimidazole
0 ImagesSynonyms: VimdemerPolyvinylimidazole (Vimdemer) is a weakly alkaline polyelectrolyte. Polyvinylimidazole can form an anticancer complex with Cadmium chloride. Polyvinylimidazole can be used as a model polyelectrolyte to study the adsorption properties of various minerals.
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3-Bromobenzoic acid
0 Images3-Bromobenzoic acid is an important intermediate that can be used in the synthesis of other active compounds. 3-Bromobenzoic acid can react with a variety of electrophiles to generate a variety of 2-substituted-3-bromobenzoic acid derivatives. 3-Bromobenzoic acid is also an effective corrosion inhibitor for aluminum in alkalized Persian Gulf seawater and NaOH solution.
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2-Hydroxymethyl benzoic acid
0 ImagesCat. No.: HY-W019358CAS No.: 612-20-42-Hydroxymethyl benzoic acid serves as an effective water substitute in the Passerini reaction. 2-Hydroxymethyl benzoic acid can be used for the synthesis of α-hydroxyamides, which are molecular building blocks for the synthesis of bioactive compounds.
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3-Amino-5-methylpyrazole
0 Images5-Methyl-1H-pyrazol-3-amine is a pyrazole heterocyclic compound and can be used as a key intermediate for the synthesis of pyrazolylamide derivatives.
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5-Bromonicotinic acid
0 Images5-Bromonicotinic acid is a brominated pyridinecarboxylic acid derivative of nicotinic acid, which serves as a pharmaceutical intermediate for organic synthesis-related research. 5-Bromonicotinic acid can form metal-organic frameworks (MOFs) with cadmium (II), cobalt (II) and lanthanide (III) salts.
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Secologanin
0 ImagesCat. No.: HY-125598CAS No.: 19351-63-4Secologanin is an iridoid monoterpenoid glucoside found in the leaves of Lonicera tatarica and a key precursor for thousands of natural monoterpenoid alkaloids.
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Acetylpyrazine
0 ImagesSynonyms: 2-AcetylpyrazineAcetylpyrazine (2-Acetylpyrazine) is used to form many polycyclic compounds, as useful structures in pharmaceuticals and perfumes. Acetylpyrazine is a component of the folates (vitamin B compounds).
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(±)-Boc-α-phosphonoglycine trimethyl ester
0 Images(±)-Boc-α-phosphonoglycine trimethyl ester serves as a glycine equivalent and glycine donor in organic synthesis.
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3-Methyluracil
0 ImagesCat. No.: HY-W140956CAS No.: 608-34-43-Methyluracil is a pyrimidine heterocyclic compound that can serve as an intermediate. 3-Methyluracil can be isolated from Cordyceps bassiana.
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(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride
0 Images(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is an intermediate in the synthesis of L-proline derivative peptides. (S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is a key raw material for the synthesis of apoptosis inhibitor protein (IAP) antagonists and SMAC mimic tripeptide fragments (Boc-MeAla-Tle-Pro-OH). (S)-Benzyl pyrrolidine-2-carboxylate hydrochloride can be used to synthesize divalent quinazoline IAP antagonists.
